NFL Week 3 Odds and Betting Lines: Bills Heavy Faves Over Dolphins on TNF

NFL Week 3 odds action kicks off tonight when the Buffalo Bills host the Miami Dolphins as 11.5-point favorites on Thursday Night Football.

The rest of the schedule is headlined by more exciting matchups between the L.A. Rams and Philadelphia Eagles, as well as an intriguing Monday matchup between the Detroit Lions and Baltimore Ravens.

Here is a look at the opening odds for NFL Week 3 and a breakdown of line movement heading into TNF.

NFL odds Week 3

Matchup	Spread	Moneyline	Over/Under
Dolphins vs Bills	Bills -11.5	Dolphins +610 Bills -900	49.5
Bengals vs Vikings	Vikings +3	Bengals +134 Vikings  -158	41.5
Packers vs Browns	Browns +7.5	Packers -420 Browns +330	41.5
Colts vs Titans	Titans +4.5	Colts -210 Titans +176	43.5
Raiders vs Commanders	Commanders -3	Raiders +138 Commanders -164	44.5
Steelers vs Patriots	Patriots +1.5	Steelers -130 Patriots +110	44.5
Falcons vs Panthers	Panthers +5.5	Falcons -250 Panthers +205	43.5
Texans vs Jaguars	Jaguars -2.5	Texans +120 Jaguars -142	44.5
Rams vs Eagles	Eagles -3.5	Rams +154 Eagles -186	44.5
Jets vs Buccaneers	Buccaneers -6.5	Jets +260 Buccaneers -320	44.5
Saints vs Seahawks	Seahawks -7.5	Saints +310 Seahawks -390	41.5
Broncos vs Chargers	Chargers -2.5	Broncos +132 Chargers -156	45.5
Cowboys vs Bears	Bears -1.5	Cowboys -108 Bears -108	50.5
Cardinals vs 49ers	49ers -2.5	Cardinals +120 49ers -142	44.5
Chiefs vs Giants	Giants +5.5	Chiefs -270 Giants +220	44.5
Lions vs Ravens	Ravens -5.5	Lions +198 Ravens -240	52.5

Lines as of 9-18

Dolphins vs Bills odds (Thursday, 8:15 p.m. ET, PRIME)

Opening line

• Bills -11.5
• Over/Under 49.5
• View full Dolphins vs. Bills odds and matchup
• Read our Dolphins vs. Bills picks and predictions

The Bills destroyed the Jets and now face another floundering AFC East rival in Miami. The Dolphins fell apart in the fourth quarter vs. New England and have a short turnaround to get right before facing Buffalo. This line opened at Bills -11.5 and quickly jumped to -12.5 before settling back to 11.5 on game day.

Also see: full Thursday Night Football odds

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Bengals vs Vikings odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Vikings -3.5
• Over/Under 44.5
• View full Bengals vs. Vikings odds and matchup
• Read our Bengals vs. Vikings picks and predictions (coming soon)

The look-ahead line listed the Vikings as 1.5-point home favorites with a total of 47.5 O/U. After Bengals QB Joe Burrow went down with a foot injury on Sunday, this line official opened Vikings -3.5, and the total dropped to 44.5. That’s down to 43.5 O/U across the board now with Burrow likely missing a major chunk of time. Minnesota also has a cluster of injuries across the offensive line and looked punchless on offense in a loss to Atlanta in Week 2.

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Packers vs Browns odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Browns +7.5
• Over/Under 42.5
• View full Packers vs. Browns odds and matchup
• Read our Packers vs. Browns picks and predictions (coming soon)

The Packers have a rest edge in Week 3 after winning on Thursday night in Week 2. This spread opened as short as -7 and moved as high as -9.5. As of Thursday morning, the market consensus is Green Bay -7.5. The total is at 41.5 O/U.

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Colts vs Titans odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Titans +3.5
• Over/Under 42.5
• View full Colts vs. Titans odds and matchup
• Read our Colts vs. Titans picks and predictions (coming soon)

The 2-0 Colts hit the road for the first time in Tennessee. Bookies opened Indianapolis as big as a 3.5-point favorite with the total at 42.5 O/U. That number has moved up to 43.5 points with the Colts' offense clicking.

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Raiders vs Commanders odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Commanders -2.5
• Over/Under 44.5
• View full Raiders vs. Commanders odds and matchup
• Read our Raiders vs. Commanders picks and predictions (coming soon)

Look-ahead lines had Washington as a 5.5-point home favorite before Las Vegas played Monday night. But with news that Commanders QB Jayden Daniels is in danger of missing Week 3 with a knee injury, the spread moved to Washington -2.5. After the Raiders lost to L.A. on MNF, this spread climbed to a field goal. This total dropped from 47.5 to 44.5 O/U on the Daniels’ news.

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Steelers vs Patriots odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Patriots +1.5
• Over/Under 43.5
• View full Steelers vs. Patriots odds and matchup
• Read our Steelers vs. Patriots picks and predictions (coming soon)

Pittsburgh opened as a 1.5-point road favorite at New England but has injuries up and down the defense, including LB Alex Highsmith. This total opened at 43.5 points and has climbed to 44.5 O/U.

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Falcons vs Panthers odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Panthers +3.5
• Over/Under 43.5
• View full Falcons vs. Panthers odds and matchup
• Read our Falcons vs. Panthers picks and predictions (coming soon)

The Falcons picked up a big win in Minnesota, and that prompted an opening spread of -3.5 at Carolina in Week 3. The line has since moved to Atlanta -5.5. This total is at 43.5 O/U

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Texans vs Jaguars odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Jaguars -1.5
• Over/Under 43.5
• View full Texans vs. Jaguars odds and matchup
• Read our Texans vs. Jaguars picks and predictions (coming soon)

Both Houston and Jacksonville lost on last-minute touchdowns in Week 2, leaving this spread somewhat unchanged from the look-ahead lines. However, the line has since jumped to JAX -2.5. This total is at 44.5 O/U.

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Rams vs Eagles odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Eagles -4.5
• Over/Under 45.5
• View full Rams vs. Eagles odds and matchup
• Read our Rams vs. Eagles picks and predictions (coming soon)

Both the Rams and Eagles were victorious in Week 2, and sportsbooks opened Philadelphia between -4 and -4.5 for this rematch of the NFC Divisional Round.Since then, it has been bet down to Eagles -3.5. This total opened at 45.5 O/U and is now 44.5.

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Jets vs Buccaneers odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Buccaneers -6.5
• Over/Under 44.5
• View full Jets vs. Buccaneers odds and matchup
• Read our Jets vs. Buccaneers picks and predictions (coming soon)

Tampa Bay came away with a big win on Monday, which officially opened this non-conference clash at Bucs -6.5. New York is holding out hope that QB Justin Fields can clear concussion protocols after leaving Week 2’s loss to Buffalo. This total opened at 44.5 O/U.

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Saints vs Seahawks odds (Sunday, 4:05 p.m. ET, CBS)

Opening line

• Seahawks -6.5
• Over/Under 41.5
• View full Saints vs. Seahawks odds and matchup
• Read our Saints vs. Seahawks picks and predictions (coming soon)

Seattle scored a win over Pittsburgh in Week 2 and opened as a 6.5-point favorite hosting New Orleans. That spread has climbed to Seahawks -7.5. This total has bounced between 41.5 and 42.5 points since opening Sunday night. 

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Broncos vs Chargers odds (Sunday, 4:05 p.m. ET, CBS)

Opening line

• Chargers -2.5
• Over/Under 45.5
• View full Broncos vs. Chargers odds and matchup
• Read our Broncos vs. Chargers picks and predictions (coming soon)

Los Angeles looks like a legit contender with a 2-0 start. The Chargers opened as 2.5-point home chalk on a short week to Denver in Week 3, with the Broncos coming off a bad loss at Indianapolis in Week 2. This total opened at 45.5 O/U.

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Cowboys vs Bears odds (Sunday, 4:25 p.m. ET, FOX)

Opening line

• Bears -1.5
• Over/Under 48.5
• View full Cowboys vs. Bears odds and matchup
• Read our Cowboys vs. Bears picks and predictions (coming soon)

Chicago is coming off a one-sided squash at the hands of the Lions and opened as 1.5-point home favorites vs. Dallas. The vig on Cowboys +1.5 is climbing, indicating a potential move to Bears -1. This total opened at 48.5 points.

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Cardinals vs 49ers odds (Sunday, 4:25 p.m. ET, FOX)

Opening line

• 49ers +1.5
• Over/Under 42.5
• View full Cardinals vs. 49ers odds and matchup
• Read our Cardinals vs. 49ers picks and predictions (coming soon)

With QB Brock Purdy doubtful for Week 3, books opened San Francisco as a 1.5-point underdog at home to Arizona. The 49ers are still missing some key weapons on offense. This total hit the board at 42.5 points and has climbed to 43.5 O/U.

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Chiefs vs Giants odds (Sunday, 8:20 p.m. ET, NBC)

Opening line

• Giants +5.5
• Over/Under 42.5
• View full Chiefs vs. Giants odds and matchup
• Read our Chiefs vs. Giants picks and predictions (coming soon)

Kansas City is 0-2 to start the season and travels to East Rutherford as 5.5-point road chalk in Week 3. This total opened at 42.5 points and jumped to 43.5 with play on the Over after New York’s offensive eruption at Dallas on Sunday.

Also see: full Sunday Night Football odds

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Lions vs Ravens odds (Monday, 8:15 p.m. ET, ABC/ESPN)

Opening line

• Ravens -5.5
• Over/Under 51.5
• View full Lions vs. Ravens odds and matchup
• Read our Lions vs. Ravens picks and predictions (coming soon)

Monday Night Football is a treat. The Ravens opened as 5.5-point home favorites vs. the Lions with the Over/Under coming out at 51.5 points. The juice on Baltimore -5.5 is rising, which could see a move to the key number of -6 later in the week. 

Also see: full Monday Night Football odds

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