Padres vs Mets Prediction, Picks & Odds — Thursday, September 18

With two so-so pitchers taking the mound this afternoon, our Padres vs. Mets predictions expect lots of action at home plate.

Tony Sartori - Contributor at Covers.com
Tony Sartori • Betting Analyst
Sep 18, 2025 • 08:23 ET • 4 min read
Information icon

This article contains predictions for an old game!

Latest MLB Picks
Juan Soto New York Mets MLB
Photo By - Imagn Images. Juan Soto reacts after hitting a home run against the Padres last night.

The New York Mets host the San Diego Padres in the final matchup of this three-game series at Citi Field. 

My Padres vs. Mets prediction focuses on the total in this NL matchup. Read on for my MLB picks for Thursday, September 18.

Padres vs Mets prediction

Padres vs Mets best bet: Over 9 (-110)

Right-handed rookie Jonah Tong takes the mound for the New York Mets, and he's struggled in his debut campaign. Through three starts, Tong is 1-2 with an 8.49 ERA and 1.71 WHIP.

His underlying metrics suggest that more of the same can be expected moving forward. If he officially qualified, Tong would rank near the bottom of the league in expected ERA (xERA), expected batting average (xBA), walk rate, and barrel rate.

These woes are likely to continue against the San Diego Padres, a team that ranks in the top half of the league in hits per game, batting average, and on-base percentage.

Meanwhile, the Padres hand the ball to right-hander Randy Vasquez. This season, he ranks in the 12th percentile or lower in xERA, xBA, strikeout rate, and barrel rate. Following Vasquez is a bullpen that ranks in the bottom half of the league in ERA and xERA.

The good news for this pitching staff is that it should receive plenty of run support. Entering this matchup, the Mets rank in the Top 10 in runs scored per game, OBP, slugging percentage, and OPS.

Padres vs Mets same-game parlay (SGP)

San Diego’s Fernando Tatis Jr. enters this game in excellent form, having crossed the plate seven times over the past four games. Tatis boasts a .500 batting average, .714 slugging percentage, and 1.325 OPS over that stretch.

Meanwhile, Juan Soto is 1-for-3 in his career against Vasquez, with that one hit being a home run.

Padres vs Mets SGP

  • Over 9
  • Fernando Tatis Over 0.5 runs
  • Juan Soto Over 0.5 runs

Padres vs Mets odds

  • Moneyline: San Diego +105 | New York -125
  • Run line: San Diego -1.5 (+165) | New York +1.5 (-200)
  • Over/Under: Over 9 | Under 9

Padres vs Mets trend

There have been 9+ total runs scored in each of Jonah Tong’s three starts. Find more MLB betting trends for Padres vs. Mets.

How to watch Padres vs Mets and game info

Location Citi Field, Queens, NY
Date Thursday, September 18, 2025
First pitch 1:10 p.m. ET
TV MLB Network
Padres starting pitcher Randy Vasquez
(5-6, 3.72 ERA)
Mets starting pitcher Jonah Tong
(1-2, 8.49 ERA)

Padres vs Mets latest injuries

Padres vs Mets weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Tony Sartori - Covers.com
Betting Analyst

Tony Sartori has written over 1,000 pieces of sports betting content across multiple different media outlets. He covers the NHL, UFC, PGA, NFL and MLB. Tony started part-time while attending the University of Wisconsin-Madison, where he went on to receive a B.A. in Economics and a certificate in Entrepreneurship in 2022. He continues to work full-time in the sports betting landscape.

Due to the variety of sports he covers, Tony is handicapping every day. If he had one piece of betting advice for a new sports bettor, it would be to strictly enforce bankroll management rules for yourself. If you set aside $10,000 for your betting bankroll, then you should generally only be betting between $100 - $500 per play.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo