The Chicago Cubs host the Arizona Diamondbacks in the final matchup of this three-game series at Wrigley Field.
My Diamondbacks vs. Cubs predictions target the total in this NL matchup. Find out why in my MLB picks for April 20.
Diamondbacks vs Cubs prediction
My Diamondbacks vs Cubs best bet: Over 7 (-120 at Caesars)
The Chicago Cubs have arguably been the best offensive team in Major League Baseball this season.
Entering this matchup, Chicago ranks in the Top 3 in the league in runs per game, hits per game, batting average, on-base percentage, slugging percentage, OPS, home runs, and stolen bases.
That success is likely to continue against right-hander Merrill Kelly, who takes the mound for the Arizona Diamondbacks. Through four starts this season, Kelly owns a 5.57 ERA and 1.33 WHIP.
His underlying metrics are even worse. Kelly ranks in the bottom quarter of the league in expected ERA (xERA), expected batting average (xBA), average exit velocity, strikeout rate, barrel rate, and hard-hit rate.
The good news for Kelly is that he should receive plenty of run support. Right-hander Jameson Taillon takes the mound for Chicago, and he's also struggled this season.
Through four starts, Taillon owns a 5.40 ERA and 1.25 WHIP. He also ranks in the bottom-third of the league in xERA, xBA, and barrel rate.
Caesars QuickPick: Our Diamondbacks vs Cubs same-game parlay (SGP)
Over 7
Ian Happ Over 0.5 total bases
Michael Busch Over 0.5 total bases
If we’re backing this game to go Over the total, we need some batters to generate offense. There may be no better candidates than Ian Happ and Michael Busch.
Happ has been tremendous, posting a .367 batting average over his past seven games. Meanwhile, Busch boasts a .406 average over that same span.
Learn how to bet a same-game parlay with these helpful tips and strategies.
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Diamondbacks vs Cubs odds
Diamondbacks vs Cubs live odds
Diamondbacks vs Cubs opening odds
- Moneyline: Arizona +110 | Chicago -130
- Run line: Arizona +1.5 (-210) | Chicago -1.5 (+175)
- Over/Under: Over 7 | Under 7
Odds courtesy of Caesars.
Diamondbacks vs Cubs trend
The Over has cashed in five of the past six meetings between these teams. Find more MLB betting trends for Diamondbacks vs. Cubs.
How to watch Diamondbacks vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Sunday, 4-20-2025 |
| First pitch | 2:20 p.m. ET |
| TV | Dbacks.TV, Marquee |
| Diamondbacks starting pitcher | Merrill Kelly (3-1, 5.57 ERA) |
| Cubs starting pitcher | Jameson Taillon (1-1, 5.40 ERA) |
Diamondbacks vs Cubs latest injuries
Diamondbacks vs Cubs weather
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